Polynucleotides (PN) treatment is an innovative and highly effective method designed to deeply hydrate, repair, and revitalize your skin at a cellular level.

This cutting-edge therapy harnesses the power of polynucleotide chains, large molecules that stimulate cellular growth and repair damaged tissues, promoting a profound healing process across the skin layers.

What are the benefits of Polynucleotides?

At a glance

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Polynucleotides are essential components for skin regeneration and repair. In my clinic, I use these naturally occurring molecules to enhance skin hydration, texture, and resilience. They are particularly effective in stimulating the body’s own healing processes, encouraging the production of collagen and elastin, which are vital for maintaining youthful, healthy skin.

The benefits of polynucleotides are extensive. They help rejuvenate the skin, improve its elasticity, and increase hydration. Over time, treatments can significantly reduce signs of aging, such as fine lines and wrinkles, and improve the overall complexion by addressing issues like dullness and uneven tone.

Polynucleotides offer a myriad of benefits for the skin, including:

  • Improved skin hydration and firmness
  • Diminished fine lines and wrinkles
  • Enhanced skin texture and radiance
  • Increased skin resilience against environmental aggressors

Polynucleotides act by promoting the skin’s regenerative processes. When introduced into the dermal layer, they stimulate the production of key skin components, leading to improved skin quality. Their ability to accelerate tissue repair and reduce inflammation makes them a powerful ally in anti-aging and skin rejuvenation.

Polynucleotides work by:

  • Providing a scaffolding effect to support skin regeneration
  • Stimulating fibroblasts to produce collagen and elastin
  • Enhancing skin hydration at a cellular level

The results from polynucleotide treatments typically start to become visible after the first few sessions, with optimal outcomes observed after a complete treatment course. The skin gradually becomes more radiant, firmer, and more hydrated as collagen and elastin levels increase.

The effects of polynucleotides become noticeable after:

  • Initial skin improvement within 2-4 weeks post-treatment
  • Optimal results typically observed after a series of sessions

In my practice, the polynucleotide treatment protocol involves a series of injections, usually administered over three sessions spaced 2-4 weeks apart. This regimen allows for sustained skin improvement, with maintenance treatments recommended every 6 to 12 months.

The typical treatment protocol involves:

  • 3 sessions spaced 2-4 weeks apart
  • Maintenance treatments every 6-12 months for sustained benefits

The effects of polynucleotide treatments can last up to 12 months, varying with individual skin conditions and lifestyles. To maintain the results, I advise periodic touch-up sessions, ensuring long-lasting skin health and hydration.

The lasting impact of polynucleotides:

  • Results can endure up to 12 months
  • Regular maintenance enhances longevity and effectiveness

Choosing between polynucleotides and Profhilo depends on individual skin concerns and desired outcomes. While both treatments offer exceptional benefits, polynucleotides are particularly favored for their regenerative properties and long-lasting hydration.

  • Polynucleotides excel in deep hydration and long-term skin repair
  • Profhilo is renowned for its immediate plumping and hydrating effect

When treating delicate areas like under the eyes, polynucleotides are applied with precision to minimize risks. Typical side effects are minor and may include slight swelling or bruising, which quickly resolves, allowing for a safe enhancement of the under-eye region.

To achieve and maintain optimal results, I recommend starting with an initial series of treatments followed by maintenance sessions every 6 to 12 months. This approach helps prolong the rejuvenating effects and supports lasting skin health.

Polynucleotides are renowned for their gentle yet effective properties, making them suitable for various skin types, including sensitive skin. In my practice, I carefully assess each client’s skin condition and tailor the treatment to ensure it is both safe and beneficial, regardless of skin sensitivity. Here’s what you should know:

  • Polynucleotides are naturally occurring substances, reducing the risk of adverse reactions.
  • They promote skin healing and are less likely to irritate compared to more invasive treatments.
  • I always conduct a detailed consultation to address any concerns and customize the treatment approach, ensuring that even clients with sensitive skin can benefit from the rejuvenating effects of polynucleotides without worry.

By choosing polynucleotide therapy at my clinic, you’re opting for a personalized and considerate approach to skin enhancement, where your comfort and skin health are my top priorities.

Not suitable for people with fish allergies, vegetarians, vegans and pregnant or breastfeeding. 


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Dr Mary Ward


Based on 6 reviews
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Susan CurleySusan Curley
19:53 03 Oct 23
I would just like to say I had a wonderful experience at Castle Aesthetics Mary is very professional at her work always listens to what you say and will never try push treatments on you .she is very friendly and welcoming will definitely be back
Carmel ByrneCarmel Byrne
16:39 20 Sep 23
Had Botox with Mary, I felt very comfortable. She never put me under any pressure to have any treatment and she really knows her stuff. I’m very happy with Castle Aesthetics and will continue to see Mary . She is a lovely down to earth person. Thanks Mary for making me feel so good about myself 😊
E BradyE Brady
14:09 20 Sep 23
"I would highly recommend Castle Aesthetics to anyone considering skin or anti ageing treatments. Mary provides an excellent service in a private and welcoming space. She is an experienced practitioner whose advice and support to her clients are exemplary. I have experienced great success with her treatments and continue to benefit from her broad range of services."
13:14 20 Sep 23
I had a few skin treatments with Dr.Mary including PRP, micro needling and lip flip. While she wasn't pushy and I wasn't under any pressure to have any procedures done, each treatment was explained to me step by step.Dr. Mary was extremely thorough, professional and knowledgeable, which made me comfortable duringtreatments. I look forward to trying out more in the near future!R.
Priyanka DahiyaPriyanka Dahiya
12:21 20 Sep 23
I recently had the pleasure of visiting Dr. Mary Ward for a skin care consultation, and I am truly in awe of her expertise and approach. Not only is she brilliant at what she does, but her ability to make her clients feel at ease is commendable. From the moment I walked in, I felt welcomed and truly heard. Dr. Ward has a natural way with people that puts you immediately at comfort, making the consultation process smooth and informative. I left her clinic not only with a clear plan for my skin but also with the assurance that I was in capable hands. Highly recommend to anyone in need of expert skin care advice and a comforting experience.
tara byrnetara byrne
11:47 20 Sep 23
I cannot recommend Mary’s treatments highly enough!Getting botox has been the best money I ever spent, I always feel very comfortable in a hygienic professional environment.Do not hesitate!! The results are amazing and no amount of skin creams will achieve those result’s! Fact!I was so nervous at the prospect and in hindsight it was totally unwarranted!Castle Aesthetics are just amazing!


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